Everybody knows that the war on drugs, as has been fought since the 1980s, has had a disproportionate negative impact on specific community: black communities, Latino communities. Everyone knows that. So, what Jeff Sessions is doing is engaged in—or he’s advocating being engaged in racial discrimination. So let’s call Jeff Sessions what he is. Jeff Sessions is a racist, if he takes on this action. It’s clear. We know it. So let’s stop playing around with it...Jeff Sessions is allowing us or is using drug policy to separate the people who we like from the people who we don’t like. And it provides a way to go after those people we don’t like, usually poor minority folks, without explicitly saying we don’t like those people. And that’s how drug law—that’s how drug law or drug policy has been enforced in this country. And so, if we allow Sessions to turn back the hands of time, then shame on all of us. The blood is on all of our hands, because we know the consequences of his proposed actions.

The main effects of smoking marijuana are contentment, relaxation, sedation, euphoria, and increased hunger, all peaking within five to fifteen minutes after smoking and lasting for about two hours...very high THC concentrations...can cause mild paranoia and visual and auditory distortions, but even these effects are rare and usually seen only in very inexperienced users.

I share my story in an effort to encourage others, especially successful professionals who are less at risk than people on the margins of society, to get out of the closet about their own drug use. If they did so, more people would see that there are far more respectable drug users than our criminal-justice regime and popular culture would have us know.

If we’re really concerned, for example, like the opioids and heroin, we need to tell people how to stay safe, if we’re worried about overdose there. About 13,000 people die every year from heroin-related overdoses, whereas 35,000 people die from automobile accidents. We don’t ban automobiles. Instead, we have regulations, and we try to make sure that people stay safe. We have speed limits. We have seat belts. We have all of these sorts of things. But with the opioids, we’re talking about arresting people. And by the way, for the opioids, at the federal level, 80 percent of the people who are arrested are Latino and black.

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I worry that people who need prescription opioids for their pain will not be able to get their prescription opioids, because we are getting crazy about opioids, in general. Opioids are excellent medications to treat pain. And we can’t forget that. We also have seen, even before this—we know that, for example, black people are less likely to be prescribed opioids even when they need it, less likely than their white counterparts. And so, all of these sort of unintended consequences, they always happen when we get crazy about drugs. And we don’t even save people.

Make sure we warn people not to combine opioids with another drug. Set up free drug purity testing sites. People who are addicted to opioids and who are having a problem, and they need treatment. We should look around the world, places like Switzerland.

one of the things that shocked me when I first started to understand what was going on, when I discovered that 80 to 90 percent of the people who actually use drugs like crack cocaine, heroin, methamphetamine, marijuana—80 to 90 percent of those people were not addicted. I thought, “Wait a second. I thought that once you use these drugs, everyone becomes addicted, and that’s why we had these problems.” That was one thing that I found out. Another thing that I found out is that if you provide alternatives to people—jobs, other sort of alternatives—they don’t overindulge in drugs like this. I discovered this in the human laboratory as well as the animal laboratory. The same thing plays out in the animal literature.

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Here's the bottom line: over my more than twenty-five-year career, I have discovered that most drug-use scenarios cause little or no harm and that some responsible drug-use scenarios are actually beneficial for human health and functioning. Even "recreational" drugs can and do improve day-to-day living.

The key is to keep the focus on people's actions, on their behaviors, rather than speculate about their motives. Trying to determine what's in a person's head or heart is a pointless distraction. It's impossible to know for certain the heart's inner secrets.

when we think about the numbers of African Americans who are in neuroscience and why—they’re low—and why the numbers are low, that’s an issue that the society hasn’t grappled with. And it’s related to some of this marijuana talk that we’re talking about. You played something about Kennedy earlier. Those kind of people, they sicken me, quite frankly, when we think about the role that racism has played in our drug enforcement, and those people don’t knowledge that? Those kind of—those types of practices have played a role in why African Americans are not in many areas in the United States.

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Each and every day, we all are faced with potential risks and must make risk-to-benefit calculations repeatedly. This is a basic fact of life. Our right to make decisions based on the outcome of these calculations is not outlawed by the government, except when it comes to certain recreational drugs. (Chapter 2)