Above all he believes that these mathematically based speculations solve thousand year old philosophical conundrums, without seriously engaging those… - George F. R. Ellis

Actually philosophical speculations have led to a great deal of good science. Einstein’s musings on Mach’s principle played a key role in developing general relativity. Einstein’s debate with Bohr and the EPR paper have led to a great of deal of good physics testing the foundations of quantum physics. My own examination of the Copernican principle in cosmology has led to exploration of some great observational tests of spatial homogeneity that have turned an untested philosophical assumption into a testable – and indeed tested - scientific hypothesis. That’ s good science.

Attempts to explain values in terms of neuroscience or evolutionary theory in fact have nothing whatever to say about what is good or bad. That is a philosophical or religious question (scientists trying to explain ethics from these kinds of approaches always surreptitiously introduce some unexamined concept of what is a good life by the back door).

"On the limits of quantum theory: Contextuality and the quantum–classical cut", Annals of Physics 327 (2012) 1890–1932