Original sin,” he said thoughtfully. “That’s about Adam an’ — no, wait. I remember. Everybody’s supposed to be sinful to start with because it takes … - Theodore Sturgeon

Reality isn’t the most pleasant of atmospheres, Lieutenant. But we like to think we’re engineered for it. It’s a pretty fine piece of engineering, the kind an engineer can respect. Drag in an obsession and reality can’t tolerate it. Something has to give; if reality goes, your fine piece of engineering is left with nothing to operate on. So it operates badly. So kick the obsession out; start functioning the way you were designed to function.

You said to imagine a great big sphere, and inside is all of time and space. All of it. And outside are these intelligent entities, and all they are is curious; all they want to do is experience.”
“Go on,” Alice said. Her eyes are so bright.…
“One might say: ‘I want the experience of being a seventeen-year-old girl in the fourteenth century who was burned at the stake.’ Or ‘I’d like the experience of being a four-month aborted fetus in 1994.’ And they just dive in and do it.” I looked at Alice. She was waiting for something. I thought about what I just said, and then I remembered: “They have to create what happens. Write a script.” She still waited, so I said, “Not only the experience itself; the house, the city, the country, the whole world where it happens. All of it.”
“Which makes that entity responsible for all of it,” she reminded me.
“So that’s who the ‘little man watching’ really is — that, that thing — ”
“Not a thing,” she said, interrupting for the very first time. “It’s you. You’re living a script that you wrote. Which is why free will and predestination are the same thing.

Create a world in which these things do or do not exist, or in which they are extended in some way. Test reality against this fiction. The reader will recognize the world that you're talking about, even though it may be another one altogether