You wake me up early in the morning to tell me that I'm right? Please wait until I'm wrong. - John von Neumann

He notes that the output of neurons is digital: an axon either fires or it doesn’t. This was far from obvious at the time, in that the output could have been an analog signal. The processing in the dendrites leading into a neuron and in the soma neuron cell body, however, are analog. He describes these calculations as a weighted sum of inputs with a threshold.

A code, which according to Turing's schema is supposed to make one machine behave as if it were another specific machine (which is supposed to make the former imitate the latter) must do the following things. It must contain, in terms that the machine will understand (and purposively obey), instructions (further detailed parts of the code) that will cause the machine to examine every order it gets and determine whether this order has the structure appropriate to an order of the second machine. It must then contain, in terms of the order system of the first machine, sufficient orders to make the machine cause the actions to be taken that the second machine would have taken under the influence of the order in question.

The calculus was the first achievement of modern mathematics and it is difficult to overestimate its importance. I think it defines more unequivocally than anything else the inception of modern mathematics; and the system of mathematical analysis, which is its logical development, still constitutes the greatest technical advance in exact thinking.