Social science is itself part of the social experience it seeks to interpret and explain. - William Hardy McNeill

John Dewey's Human Nature and Conduct...What struck me... was the related idea that human thought is a reaction to frustrated habit— what people often do when the outcome of their action disappoints their expectation. I concluded that unthinking, habitual action is the natural and truly happy way of life; whereas thought is a symptom of dysfunction but conducive to survival all the same since, every so often, new thoughts find ways of escaping the frustration that provoked them by inventing satisfying new ways to get things done.

In 1933-34, I took a full-blown college course on the University of Chicago campus. This was part of an experiment by President Hutchins to see whether combining the last two years of high school with the first two years of college might make a more rigorous curriculum possible for what he called "General Education." This he hoped might provide a rational, philosophical guide to adult life and citizenship, replacing the vanished religious certainties he had grown up to reject—and regret.

Ingenuity, knowledge, and organization alter but cannot cancel humanity's vulnerability to invasion by parasitic forms of life. Infectious disease which antedated the emergence of humankind will last as long as humanity itself, and will surely remain, as it has been hitherto, one of the fundamental parameters and determinants of human history.