The law which asserts that the equation X = 0, complete or incomplete, can have no more real positive roots than it has changes of sign, and no more … - David Eugene Smith

Cardan's originality in the matter seems to have been shown chiefly in four respects. First, he reduced the general equation to the type <math>x^3 + bx = c</math>; second, in a letter written August 4, 1539, he discussed the question of the irreducible case; third, he had the idea of the number of roots to be expected in the cubic; and, fourth, he made a beginning in the theory of symmetric functions. ...With respect to the irreducible case... we have the cube root of a complex number, thus reaching an expression that is irreducible even though all three values of x turn out to be real. With respect to the number of roots to be expected in the cubic... before this time only two roots were ever found, negative roots being rejected. As to the question of symmetric functions, he stated that the sum of the roots is minus the coefficient of x²

His writings include works on mechanics, sound, astronomy, the tides, the laws of motion, the Torricellian tube, botany, physiology, music, the calendar (in opposition to the Gregorian reform), geology, and the compass,—a range too wide to allow of the greatest success in any of the lines of his activity. He was also an ingenious cryptologist and assisted the government in deciphering diplomatic messages.

When we speak of the early history of algebra it is necessary to consider... the meaning of the term. If... we mean the science that allows us to solve the equation <math>ax^2 + bx + c = 0</math>, expressed in these symbols, then the history begins in the 17th century; if we remove the restriction as to these particular signs, and allow for other and less convenient symbols, we might properly begin the history in the 3rd century; if we allow for the solution of the above equation by geometric methods, without algebraic symbols of any kind, we might say that algebra begins with the or a little earlier; and if we say that we should class as algebra any problem that we should now solve with algebra (even though it was as first solved by mere guessing or by some cumbersome arithmetic process), the science was known about 1800 B.C., and probably still earlier.<