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Today, wonderful operations can be performed on babies to repair heart defects. This includes "blue babies." During the corrective procedure, high le… - Gerald Buckberg
" "Today, wonderful operations can be performed on babies to repair heart defects. This includes "blue babies." During the corrective procedure, high levels of oxygen are typically administered by a heart-lung machine... But... lung and heart damage may worsen. ...[O]ne cause of the problem were the high levels of oxygen administered ...as toxic substances are produced when such oxygen concentrations are metabolized. Babies are particularly vulnerable... Yet we found this "re-oxygenation injury" could be avoided by lowering oxygen levels delivered... There was excellent recovery of heart function without lung or body swelling. ...A 2012 overview on reoxygenation injury was published in the World Journal for Pediatric and Congenital Heart Surgery that summarized international papers from others... [R]aising such questions to traditionalists garners vehement rejection, along with counterarguments that keeping oxygen levels high is a strategy ..."proven..." over many decades (since not all blue babies suffer damage...) They perceive the greater risk is losing the baby because of "insufficient... oxygen"... and... blame... unforeseen complications on other factors.
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About Gerald Buckberg
(September 29, 1935 - September 20, 2018) was a Distinguished Professor of Surgery, Division of Cardiothoracic Surgery, at the . His research interests initially centered in the area of myocardial protection and led to the introduction of blood , which is currently used by over 85% of surgeons in the United States and 75% of surgeons worldwide for adult and pediatric heart operations. He was a member of multiple surgical societies, including the , , and the .
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Additional quotes by Gerald Buckberg
An alternate and effective three-step approach has been used experimentally... First, CPR specifically designed to provide sufficient blood pressure is employed to ensure blood nourishment to the brain. Second, body circulation is supported using a small portable heart-lung machine whose catheters easily access the groin arteries. ...Third, the dead heart is then brought back to life by the delivery of blood containing ...added ingredients ...[T]his new method was applied internationally to 34 sudden death patients. ...80% ...survived ...only one patient sustained brain injury. ...[W]ith present methods... 100% will die if CPR/defibrillation does not return an efficient heartbeat within 15 minutes. Yet these 34 patients underwent CPR for an average of 72 minutes... Because it also treated the cause behind the sudden death and not just the symptom (the heart stopping).
Stopping the heart is accomplished by shutting off its blood supply (a process called ). I discovered blood ... We initally realized the return of regular blood to a heart that has been without blood supply, will create severe damage. We then discovered how to prevent this injury by using a blood cardioplegic solution that contains selected chemical ingredients (including key amino acids...)that safely protects the heart... [E]ffectiveness... depended upon their arriving at specific locations... But many of our patients had narrowed arteries... This barrier was overcome by delivering it in a "backward direction" via the heart’s main vein... further enhanced by administering it at different temperatures during the beginning and end of the operation.
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