Just as nobody pursues happiness in order to find anything other than happiness, so nobody strives to reduce pain to reduce anything other than pain.… - Richard D. Ryder

Consciousness is of paramount importance to all of us. By definition it is the universe of our awareness. On the assumption that many other species are conscious or sentient I have suggested that our morality is based upon a concern for all sentients-which I have called sentientism, although I could equally have called it consciousism (but that is even more horrible as a word!). Pain and pleasure are the two great poles of consciousness, between which all sentients swing ... .

Differences in reaction to toxic substances vary considerably between species so that the value of these tests remains doubtful. Although thalidomide was extensively tested on animals in several countries, its terrible properties were not discovered. Conversely, penicillin, the greatest medical discovery of the century, was not extensively tested on animals before its miraculous therapeutic qualities were demonstrated in human patients. If it had been fully tested on animals its high toxicity for guinea pigs would have almost certainly prevented its clinical use.

We have an obligation to try to reduce the pains of others, wherever they are, and however the pains have been caused.