We also have a power to destroy the earth, and... it's probably unique. ...Destroy ourselves, destroy a large part of life in earth, not the bacteria… - Nick Lane

I'm... interested in the principles of what governs the emergence of life on the planet, with a certain set of resources. Can we understand it? We'll never know what happened, so we'll never know how life started on earth. ...[I]f those principles are enormously difficult, if it turns out that it's a freak statistical accident, then there's little point in studying it and we will gain... very little. If, on the other hand, those principles are reasonable, intelligible, that we can study them in the lab and demonstrate that the steps that we propose are plausible and... we can demonstrate it, then I think that's as close to understanding the origin of life [as] we can get. ...[I]f those principles are generalizable, then as a scientist, that's... a pleasing thing. I'm not sure there's any more that's more pleasing to me, personally as a scientist.

[T]here's a limit to just how far vents can take you... but... once you've gotten as far as , then you've freed yourself from a fairly small energy flow, a fairly tight and focused energy flow.

I deliberately avoid having... [a working definition of life]. What I quote... is... from Peter Mitchell... a pioneer... of... , that essentially all cells, with very very few exceptions, are powered by... proton gradients across the membrane. So on one side of the membrane surrounding the cell you've got the high concentration on the inside, a low proton concentration [on the outside]. Protons are... the positively charged nuclei of atoms, so... [y]ou're pumping them out and... putting a charge on the membrane... That's as universally conserved across life on earth as the itself, which implies, as a mechanism, it's very early... [I]t's not something anyone ever predicted. It's not something that... emerges from a chemical understanding of the biochemistry of cells.