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" "[I]n Houston (and elsewhere in Texas) is an area known as the Fifth Ward... Driving... deep into this neighborhood reminded me of the terrible poverty I had seen... in destitute areas of Honduras, Guatemala, Brazil, and China. I saw... images... just like the standard global disease movie typically shown to first-year public health or medical students. ...It was even more astonishing when we turned our global health lens inward to study diseases that were infecting impoverished areas... [W]e found widespread NTDs... in Texas and elsewhere in the southern United States. ...NTDs are first and foremost diseases of acute poverty. ...[W]e determined that 12 million Americans who live at such poverty levels suffer from at least one NTD. The diseases include neglected parasitic infections such as , , , and .
(born 5 May 1958) is an American scientist, pediatrician, and advocate in the fields of , vaccinology, and neglected tropical disease control. He serves as founding dean of the National School of Tropical Medicine and Professor of Pediatrics and Molecular Virology & Microbiology at , where he is also Director of the Center for Vaccine Development and Texas Children’s Hospital Endowed Chair in Tropical Pediatrics. Hotez served previously as President of the and is a founding Editor-in-Chief of . He is also the co-director of Parasites Without Borders, a global nonprofit organization with a focus on those suffering from parasitic diseases in subtropical environments.
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So we have a vaccine now in clinical trials, a vaccine that we hope will advance to the clinic soon, a Hookworm vaccine in clinical trials, a new vaccine that's moving into the clinic. I like to say that these are the most important diseases that you've never heard of. These are some of the most common afflictions of the world's population, but they mostly occur among people who live in extreme poverty... [S]o there is no model to figure out who's going to pay for them. So as a consequence, neither the biotechs nor the big pharmaceutical companies make those vaccines.