It's much harder to be relevant than it is to be successful - Bono

There's stuff you can learn from people who don't tell you anything.

I'm less unsure about taking political risks or social risks. When I became an activist, people were like, "Really?" But they eventually accepted that. Then I started to be interested in commerce and the machinery of what got people out of poverty and into prosperity. And then a few people said, "You can't really go there, can you?" I said, "But if you are an artist, you must go there." You and I have had the conversation over the years: What can the artist do? What is the artist not allowed to do, and are there boundaries? Now, I would say to my younger self: "Experiment more and don't let people box you in. There is nothing you can't put on your canvas if it is part of your life."

The scale of the suffering and the scope of the commitment they often numb us into a kind of indifference. Wishing for the end to AIDS and extreme poverty in Africa is like wishing that gravity didn't make things so damn heavy. We can wish it, but what the hell can we do about it? Well, more than we think. We can't fix every problem — corruption, natural calamities are part of the picture here — but the ones we can we must. The debt burden, as I say, unfair trade, as I say, sharing our knowledge, the intellectual copyright for lifesaving drugs in a crisis, we can do that. And because we can, we must. Because we can, we must. Amen.