It is in the nature of science that once a position becomes orthodox it should be subjected to criticism.... It does not follow that, because a posit… - John Maynard Smith

Paradoxically, it has turned out that game theory is more readily applied to biology than to the field of economic behavior for which it was originally designed

The theory of games was first formalised by Von Neumann & Morgenstern (1953) in reference to human economic behaviour. Since that time, the theory has undergone extensive development... Sensibly enough, a central assumption of classical game theory is that the players will behave rationally, and according to some criterion of self-interest. Such an assumption would clearly be out of place in an evolutionary context. Instead, the criterion of rationality is replaced by that of population dynamics and stability, and the criterion of self-interest by Darwinian fitness.

Darwin's theory of evolution by natural selection is the only workable explanation that has ever been proposed for the remarkable fact of our own existence, indeed the existence of all life wherever it may turn up in the universe.