No substance in nature, as far as yet known, has, when it reaches the brain, such power to induce mental and moral changes of a disastrous character … - Timothy Shay Arthur

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No substance in nature, as far as yet known, has, when it reaches the brain, such power to induce mental and moral changes of a disastrous character as alcohol. Its transforming power is marvelous, and often appalling. It seems to open a way of entrance into the soul for all classes of foolish, insane or malignant spirits, who, so long as it remains in contact with the brain, are able to hold possession.