When the Chinese started putting up the data on Bioarchive in January-February, we saw a very close homology between the two, and realized that we ma… - Peter J. Hotez

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When the Chinese started putting up the data on Bioarchive in January-February, we saw a very close homology between the two, and realized that we may be sitting on a very attractive Coronavirus vaccine. Now, we're working... again with NIH, and we're working with BARDA and others to get the funding, but now we'll have that lag. ...[T]hese clinical trials are not going to go that quickly because of that immune enhancement. It's going to take time. ...[U]nfortunsately, some of my colleagues in the biotech industry are making these inflated claims. ...[Y]ou've seen this... in the newspapers, "We're going to have this vaccine in weeks..." What they're really seeing is that they can move a vaccine into clinical trials, but this will not go quickly because as we start vaccinating human volunteers, especially in areas where we have community transmission, we're going to have to proceed very slowly, very cautiously. The FDA is on top of that. They have a great team in place at the . They're aware of the problem, but it's not going to go quickly. We are going to have to follow this very slowly, cautiously, to make certain that we're not seeing that immune enhancement. So now we're hearing projections, a year, 18 months, who knows...

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About Peter J. Hotez

(born 5 May 1958) is an American scientist, pediatrician, and advocate in the fields of , vaccinology, and neglected tropical disease control. He serves as founding dean of the National School of Tropical Medicine and Professor of Pediatrics and Molecular Virology & Microbiology at , where he is also Director of the Center for Vaccine Development and Texas Children’s Hospital Endowed Chair in Tropical Pediatrics. Hotez served previously as President of the and is a founding Editor-in-Chief of . He is also the co-director of Parasites Without Borders, a global nonprofit organization with a focus on those suffering from parasitic diseases in subtropical environments.

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Alternative Names: Peter J Hotez Peter Hotez P. J. Hotez P J Hotez P. Hotez P Hotez Hotez P Hotez P. Hotez P. J. Hotez PJ Peter Jay Hotez
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Additional quotes by Peter J. Hotez

But we collaborated with a unique group that figured out how to solve the problem. That if you narrow it down to the smallest subunit, the piece that... [is] called the receptor binding domain, that docs with the receptor, you get protection, and you don't get that immune enhancement phenomenon. ...We proposed this to the . They funded it and we wound up actually making and manufacturing, in collaboration with , a first generation SARS vaccine. So SARS was the one that emerged in 2003... and then this new one... we call the SARS 2 Coronavirus. We had it manufactured, but then we could never get the investment to take it beyond that. ...We had the vaccine ready to go, but we couldn't move it into the clinic, because of lack of funding, because by then nobody was interested in Coronavirus vaccines.

One reason... to move our scientists to Houston was to take advantage of being located within the [TMC]... comprising more than 50 biomedical institutions and 100,000 employees, occupying a building space that exceeds that of downtown Los Angeles. A second reason... generous support from Texas Children's Hospital (the world's largest...) which also housed the Sabin Vaccine Institute PDP... Our goal for moving and becoming linked to the TMC was to increase the number of new vaccines we are creating for the poorest people in less developed countries, [and] to accelerate the pace at which they are produced. ...[T]oday we have two vaccines in clinical trials—with others in various stages of development.

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