The mental never influences the physical. It is always the physical that modifies the mental, and when we think that the mind is diseased, it is alwa… - Claude Bernard

[I]t is important to determine at what point to apply doubt, so as to distinguish it from scepticism, and to show how scientific doubt becomes an element of the greatest certainty. The sceptic disbelieves in science and believes in himself; he believes enough in himself to dare deny science and to assert that it is not subject to definite, fixed laws. The doubter is a true man of science; he doubts only himself and his interpretations, but he believes in science; in the experimental sciences, he even accepts a criterion of absolute scientific principle.

[T]he experimental method draws from within itself an impersonal authority which dominates science. It forces this authority even on great men.[…] Every period has its own sum total of errors and of truths. Certain mistakes are, in a sense, inherent in their period, so that only the subsequent progress of science can reveal them.… [T]he further science advances, the more it takes an impersonal form and detaches itself from the past.

In sciences of observation, man observes and reasons experimentally, but he does not experiment; and in this sense we might say that a science of observation is a passive science. In sciences of experimentation, man observes, but in addition he acts on matter, analyzes its properties and to his own advantage brings about the appearance of phenomena which doubtless always occur according to natural laws, but in conditions which nature often has not yet achieved. With the help of these active experimental sciences, man becomes an inventor of phenomena, a real foreman of creation: and under this head we cannot set limits to the power that he may gain over nature through future progress in the experimental sciences.