Even if there is only one possible unified theory, it is just a set of rules and equations. What is it that breathes fire into the equations and make… - Stephen Hawking

For millions of years, mankind lived just like the animals. Then something happened which unleashed the power of our imagination. We learned to talk and we learned to listen. Speech has allowed the communication of ideas, enabling human beings to work together to build the impossible. Mankind's greatest achievements have come about by talking, and its greatest failures by not talking. It doesn't have to be like this. Our greatest hopes could become reality in the future. With the technology at our disposal, the possibilities are unbounded. All we need to do is make sure we keep talking.

The uncertainty principle signaled an end to Laplace’s dream of a theory of science, a model of the universe that would be completely deterministic: one certainly cannot predict future events exactly if one cannot even measure the present state of the universe precisely! We could still imagine that there is a set of laws that determine events completely for some supernatural being, who could observe the present state of the universe without disturbing it.

Einstein is the only figure in the physical sciences with a stature that can be compared with Newton. Newton is reported to have said "If I have seen further than other men, it is because I stood on the shoulders of giants." This remark is even more true of Einstein who stood on the shoulders of Newton. Both Newton and Einstein put forward a theory of mechanics and a theory of gravity but Einstein was able to base General Relativity on the mathematical theory of curved spaces that had been constructed by Riemann while Newton had to develop his own mathematical machinery. It is therefore appropriate to acclaim Newton as the greatest figure in mathematical physics and the Principia is his greatest achievement.