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" "Stopping the heart is accomplished by shutting off its blood supply (a process called ). I discovered blood ... We initally realized the return of regular blood to a heart that has been without blood supply, will create severe damage. We then discovered how to prevent this injury by using a blood cardioplegic solution that contains selected chemical ingredients (including key amino acids...)that safely protects the heart... [E]ffectiveness... depended upon their arriving at specific locations... But many of our patients had narrowed arteries... This barrier was overcome by delivering it in a "backward direction" via the heart’s main vein... further enhanced by administering it at different temperatures during the beginning and end of the operation.
(September 29, 1935 - September 20, 2018) was a Distinguished Professor of Surgery, Division of Cardiothoracic Surgery, at the . His research interests initially centered in the area of myocardial protection and led to the introduction of blood , which is currently used by over 85% of surgeons in the United States and 75% of surgeons worldwide for adult and pediatric heart operations. He was a member of multiple surgical societies, including the , , and the .
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[N]ot only does the fingertip have a spiral, but [there is] the spiral at the tip of your heart. Perhaps the tip of your heart is your apical fingertip. ...The ventricle, which is the beating part of the heart, has a spiral... it goes from inside-out, and outside-in. That spiral is very typical. It goes down to the apex of the heart, the tip of the heart, which is a vortex. The thing that really makes the heart a part of an active way of living.
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[I]f you look at the diseases we see... a narrowing in the coronary artery... a valve becomes leaky, either the or the , or people who have muscular disease. The heart changes from an ellipse to a sphere. In a sense... from a football to a basketball. ...[T]here's alteration in the fiber direction of the ventricle.