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" "Stopping the heart is accomplished by shutting off its blood supply (a process called ). I discovered blood ... We initally realized the return of regular blood to a heart that has been without blood supply, will create severe damage. We then discovered how to prevent this injury by using a blood cardioplegic solution that contains selected chemical ingredients (including key amino acids...)that safely protects the heart... [E]ffectiveness... depended upon their arriving at specific locations... But many of our patients had narrowed arteries... This barrier was overcome by delivering it in a "backward direction" via the heart’s main vein... further enhanced by administering it at different temperatures during the beginning and end of the operation.
(September 29, 1935 - September 20, 2018) was a Distinguished Professor of Surgery, Division of Cardiothoracic Surgery, at the . His research interests initially centered in the area of myocardial protection and led to the introduction of blood , which is currently used by over 85% of surgeons in the United States and 75% of surgeons worldwide for adult and pediatric heart operations. He was a member of multiple surgical societies, including the , , and the .
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I picked up a book [The Illustrations from the Works of Andreas Vesalius of Brussels ed., Saunders & O'Malley] on Vesalius... [H]e cut the heart... to see the different cavities... in the 1500s. ...[T]he cardiac structure is the first example since Leonardo da Vinci showing the thickness of the walls and the shape of the cavities.
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[I]f you look at the helical heart, you see a hidden harmony of spirals. You see the DNA... the blueprint... You see the ventricle... You see that you have ejection and suction with the spirals going in different directions, with the spirals within spirals. You see it in the microscopic structure of the heart, the different forms of the heart called the , , , <nowiki>[</nowiki>]... It's all the same. It's a reproduction of what is normal and very efficient.