Such delusions of grandeur to think that a God with a hundred billion galaxies on his mind would give a tuppenny damn who you sleep with, or indeed w… - Richard Dawkins

We are survival machines-robot vehicles blindly programmer to preserve the selfish molecules known as genes. This is a truth which still fills me with astonishment. Though I have known it for years, I never seem to get fully used to it.

Don't ever be lazy enough, defeatist enough, cowardly enough to say “I don't understand it so it must be a miracle - it must be supernatural - God did it”. Say instead, that it's a puzzle, it's strange, it's a challenge that we should rise to. Whether we rise to the challenge by questioning the truth of the observation, or by expanding our science in new and exciting directions - the proper and brave response to any such challenge is to tackle it head-on. And until we've found a proper answer to the mystery, it's perfectly ok simply to say “this is something we don't yet understand - but we're working on it”. It's the only honest thing to do. Miracles, magic and myths, they can be fun. Everybody likes a good story. Myths are fun, as long as you don't confuse them with the truth. The real truth has a magic of its own. The truth is more magical, in the best and most exciting sense of the word, than any myth or made-up mystery or miracle. Science has its own magic - the magic of reality.

The wheel may be one of those cases where the engineering solution can be seen in plain view, yet be unattainable in evolution because it lies [on] the other side of a deep valley, cutting unbridgeably across the massif of Mount Improbable.