In a perfect world an idea could be born, nourished, developed and made known to everyone, criticized and perfected, and put to good use without the … - Warren Weaver

Is science really gaining in its assault on the totality of the unsolved? As science learns one answer, it is characteristically true that it also learns several new questions. It is as though science were working in a great forest of ignorance, making an ever larger circular clearing within which, not to insist on the pun, things are clear... But as that circle becomes larger and larger, the circumference of contact with ignorance also gets longer and longer. Science learns more and more. But there is an ultimate sense in which it does not gain; for the volume of the appreciated but not understood keeps getting larger. We keep, in science, getting a more and more sophisticated view of our essential ignorance.

Science has led to a multitude of results that affect men's lives. Some of these results are embodied in mere conveniences of a relatively trivial sort. Many of them, based on science and developed through technology, are essential to the machinery of modern life. Many other results, especially those associated with the biological and medical sciences, are of unquestioned benefit and comfort. Certain aspects of science have profoundly influenced men's ideas and even their ideals. Still other aspects of science are thoroughly awesome.

Is a virus a living organism? What is a gene, and how does the original genetic constitution of a living organism express itself in the developed characteristics of the adult? Do complex protein molecules "know how" to reduplicate their pattern, and is this an essential clue to the problem of reproduction of living creatures? All these are certainly complex problems, but they are not problems of disorganized complexity, to which statistical methods hold the key. They are all problems which involve dealing simultaneously with a sizable number of factors which are interrelated into an organic whole. They are all, in the language here proposed, problems of organized complexity.