What makes our existence meaningful is highly subjective and ultimately determined by sustainable neurochemical gratification. - Nayef Al-Rodhan

Indeed, collective triumph will also depend both on the application of reason and the recognition that a great deal of knowledge is indeterminate and may be temporally, spatially and perhaps culturally constrained.

One challenge is to agree on minimum criteria of good governance that are not perceived as a threat to cultural traditions and to draw on moral concepts that are indigenous to specific cultural settings. {{fix cite}

Human nature as we know it is, nevertheless, malleable and manageable. It may be radically modified as a result of advances in bio-, molecular, nano- and computational technologies. It will therefore be essential to establish a clear code of ethics regulating the use of these technologies sooner rather than later.