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" "Nearly every doctor I worked with dreamed as a child about curing disease and worked like crazy to become a doctor. They studied tirelessly to learn science, entered medical school with idealistic visions, and became the pride of their family. They entered residency with hundreds of thousands of dollars of student loan debt and initially saw the chronic sleep deprivation and verbal abuse by their superiors as integral parts of the experience — because “great achievement is born of great sacrifice.” But almost universally among doctors I have met, this idealism eventually turns to cynicism. My colleagues in residency talked often about questioning their sanity, of wondering whether this was all worth it. I spoke with successful surgeons who’d drafted their resignation letters dozens of times. Another had a recurring daydream of leaving everything behind and becoming a baker. Many of my supervising physicians were desperate to spend more time with their children. I witnessed more than one tearful breakdown in the operating room when surgical cases were delayed and led to yet another missed bedtime for their kids. Several had dealt with suicidal depression. I understood why doctors had the highest burnout and suicide rate of any profession. Inevitably, these conversations led to an insight that I believe is whispered by doctors in every hospital in America: they feel trapped inside a broken system.
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Our modern diets and lifestyles are synergistically ravaging our mitochondria. Our mitochondria and the greater cells that house them co-evolved over eons in relationship with our environment. Their mechanisms work in connection with a combination of inputs and information that come from the outside world into our bodies and ultimately into them. Certain kinds of nutrients, sunlight, and information from bacteria in the gut, among other things, all help trigger or supply the cells and their powerhouses with what they require to work. But many of those inputs and information streams have changed radically, resulting in blocks to proper mitochondrial function and downright damage to
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He observed that when we build rockets we put over 10,000 sensors on them to understand the functioning of all parts of the spacecraft and to enable prediction of mechanical dysfunction and systems failure before it happens... Yet with human health, we adhere to an opposite paradigm. We wait for the human body to develop fulminant systems failure, which shows up as symptoms and meeting diagnostic thresholds for disease-specific biomarkers.