Self-interest is not myopic selfishness. It is whatever it is that interests the participants, whatever they value, whatever goals they pursue. The scientist seeking to advance the frontiers of his discipline, the missionary seeking to convert infidels to the true faith, the philanthropist seeking to bring comfort to the needy - all are pursuing their interests, as they see them, as they judge them by their own values.

A theory of necessary conditions will tend to generate a model of the open society, whereas a theory of necessary and sufficient conditions will tend to generate a model of the closed society. These conflicting models result from the inner logic of ideas. To offer a sketch of what is minimally necessary for a good society is to leave considerable room for diversity, variation, and change. But the available space for individuality will progressively decrease as additional details transform what had been a sketch into a veritable blueprint for the good society.

It is not a correct deduction from the Principles of Economics that enlightened self-interest always operates in the public interest. Nor is it true that self-interest generally is enlightened; more often individuals acting separately to promote their own ends are too ignorant or too weak to attain even these.

Self-interest, or rather self-love, or egoism, has been more plausibly substituted as the basis of morality. But I consider our relations with others as constituting the boundaries of morality. With ourselves, we stand on the ground of identity, not of relation, which last, requiring two subjects, excludes self-love confined to a single one. To ourselves, in strict language, we can owe no duties, obligation requiring also two parties. Self-love, therefore, is no part of morality. Indeed, it is exactly its counterpart.

The methodological strategy of using the concept of rationality as an 'intermediary' is particularly inappropriate in arriving at the proposition that actual behaviour must be self-interest maximizing. Indeed, it may not be quite as absurd to argue that people always actually do maximize their self-interest, as it is to argue that rationality must invariably demand maximization of self-interest. Universal selfishness as actuality may well be false, but universal selfishness as a requirement of rationality is patently absurd.

The simplified notion of self-interest used by our political and social science cannot tolerate the tension between one’s own and the good, for that tension leaves human behavior unpredictable. One cannot penetrate into every individual’s private thoughts, and there is no clear way to judge among different conceptions of the good. So in order to overcome the tension, science tries to combine one’s own and the good in such a way as to preserve neither. It generalizes one’s own as the interest of an average or, better to say, predictable individual who lives his life quantifiably so as to make its study easier for the social scientist. And for the same purpose it vulgarizes the good by eliminating the high and the mighty in our souls (not to mention the low and vicious), transforming our aspiration to nobility and truth into personal preferences of whose value science is incognizant, to which it is indifferent.

Politically, economically and philosophically the motive of self-interest not only is but must...and ought to be the mainspring of human conduct...For as long a time as the records of history have been preserved human societies passed through a ceaseless process of evolution and adjustment. This process has sometimes been pacific, but more often it has resulted from warlike disturbance. The strength of different nations, measured in terms of arms, varies from century to century. The world continues to offer glittering prizes to those who have stout hearts and sharp swords; it is therefore extremely improbable that the experience of future ages will differ in any material respect from that which has happened since the twilight of the human race … it is for us who, in our history have proved ourselves a martial … people … to maintain in our own hands the adequate means for our own protection and … to march with heads erect and bright eyes along the road of our imperial destiny.

Morality, if present, should not be relied on because it will be trumped by self interest in most circumstances.

the world’s interactions with Africa are not necessarily motivated by altruism, but by the self-interest of states seeking to maximize their opportunities and minimize their costs, often at the expense of those who are not in a position to do either.

Although Americans justify their self-interest in moral terms, their true interest is never itself moral.

At first it was built up around the self-interest of the family unit. Later the ring-pass-not enlarged to include the tribe. The tribal communities finally produced the small state or nation. The aggressive self-interest of nations eventually produced Empires. Everything outside of the Empire was potential enemy or potential prey.

The poor man retains the prejudices of his forefathers without their faith, and their ignorance without their virtues; he has adopted the doctrine of self-interest as the rule of his actions, without understanding the science which puts it to use; and his selfishness is no less blind than was formerly his devotedness to others. If society is tranquil, it is not because it is conscious of its strength and its well-being, but because it fears its weakness and its infirmities; a single effort may cost it its life. Everybody feels the evil, but no one has courage or energy enough to seek the cure. The desires, the repinings, the sorrows, and the joys of the present time lead to no visible or permanent result, like the passions of old men, which terminate in impotence.

A small knowledge of human nature will convince us, that, with far the greatest part of mankind, interest is the governing principle; and that almost every man is more or less, under its influence. Motives of public virtue may for a time, or in particular instances, actuate men to the observance of a conduct purely disinterested; but they are not of themselves sufficient to produce persevering conformity to the refined dictates and obligations of social duty. Few men are capable of making a continual sacrifice of all views of private interest, or advantage, to the common good. It is vain to exclaim against the depravity of human nature on this account; the fact is so, the experience of every age and nation has proved it and we must in a great measure, change the constitution of man, before we can make it otherwise. No institution, not built on the presumptive truth of these maxims can succeed.

The needs of a society determine its ethics.