They had not been there many days when the plague broke out at Athens for the first time. A similar disorder is said to have previously smitten many … - Thucydides

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They had not been there many days when the plague broke out at Athens for the first time. A similar disorder is said to have previously smitten many places, particularly Lemnos, but there is no record of such a pestilence occurring elsewhere, or of so great a destruction of human life. For a while physicians, in ignorance of the nature of the disease, sought to apply remedies; but it was in vain, and they themselves were among the first victims, because they oftenest came into contact with it. No human art was of any avail, and as to supplications in temples, enquiries of oracles, and the like, they were utterly useless, and at last men were overpowered by the calamity and gave them all up.

(Book 2 Chapter 47.3-4)