Slavery is the ultimate form of being ripped from one's context, and thus from all the social relationships that make one a human being. - David Graeber

To take what might seem an "objective", macro-economic approach to the origins of the world economy would be to treat the behavior of early European explorers, merchants, and conquerors as if they were simply rational responses to opportunities—as if this were just what anyone would have done in the same situation. This is what the use of equations so often does: make it seem perfectly natural to assume that, if the price of silver in China is twice what it is in Seville, and inhabitants of Seville are capable of getting their hands on large quantities of silver and transporting it to China, then clearly they will, even if doing so requires the destruction of entire civilizations. Or if there is a demand for sugar in England, and enslaving millions is the easiest way to acquire labor to produce it, then it is inevitable that some will enslave them.

Karl Marx, who knew quite a bit about the human tendency to fall down and worship our own creations, wrote Das Capital in an attempt to demonstrate that, even if we start from the economists' utopian vision, so long as we also allow some people to control productive capital, and, again, leave others with nothing to sell but but their brains and bodies, the results will be in very many ways barely distinguishable from slavery, and the whole system will eventually destroy itself.

If we insist on defining all human interactions as matters of people giving one thing for another, then any ongoing human relations can only take the form of debts.