So all life is a great chain, the nature of which is known whenever we are shown a link of it. - Arthur Conan Doyle

...I cannot live without brain-work. What else is there to live for? Stand at the window here. Was ever such a dreary, dismal, unprofitable world? See how the yellow fog swirls down the street and drifts across the dun-colored houses. What could be more hopelessly prosaic and material? What is the use of having powers, doctor, when one has no field upon which to exert them? Crime is commonplace, existence is commonplace, and no qualities save those which are commonplace have any function upon earth.

There's many a man who never tells his adventures, for he can't hope to be believed.

Watson: When do we start?
Holmes: You are not coming.
Watson: Then you are not going. I give you my word of honour - and I never broke it in my life - that I will take a cab straight to the police station and give you away unless you let me share this adventure with you.