Saw a down-and-out in Seattle last night. His sign said not "I need food" or "I need a job" but "I need a fat bitch". What could this mean? - Richard Dawkins

We, alone on earth, can rebel against the tyranny of the selfish replicators.

When we look at a solid lump of iron or rock, we are 'really' looking at what is almost entirely empty space. It looks and feels solid and opaque because our sensory systems and brains find it convenient to treat it as solid and opaque. It is convenient for the brain to represent a rock as solid because we can't walk through it. 'Solid' is our way of experiencing things that we can't walk through or fall throug, because of the electromagnetic forces between atoms. 'Opaque' is the experience we have when light bounces off the surface of an object, and none of it goes through.

There's nothing nonsensical about saying that what would evolve if Darwinian selection has its head is something that you don't want to happen. And I could easily imagine trying to go against Darwinism.