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Our modern diets and lifestyles are synergistically ravaging our mitochondria. Our mitochondria and the greater cells that house them co-evolved over… - Casey Means
" "Our modern diets and lifestyles are synergistically ravaging our mitochondria. Our mitochondria and the greater cells that house them co-evolved over eons in relationship with our environment. Their mechanisms work in connection with a combination of inputs and information that come from the outside world into our bodies and ultimately into them. Certain kinds of nutrients, sunlight, and information from bacteria in the gut, among other things, all help trigger or supply the cells and their powerhouses with what they require to work. But many of those inputs and information streams have changed radically, resulting in blocks to proper mitochondrial function and downright damage to
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Continuous Glucose Monitoring I believe CGM is the most powerful technology for generating the data and awareness to rectify our Bad Energy crisis in the Western world. A CGM is a biosensor that can alert us to early dysfunction, coach us on how to eat and live in a way that promotes Good Energy in our unique bodies, and promote accountability. My belief in the potential of this technology to reduce global metabolic suffering is why I cofounded Levels, which enables access to CGMs and software to understand and interpret the data. A CGM is a small plastic disc worn on the arm that automatically tests your blood sugar roughly every ten minutes, twenty-four hours a day. And it sends that information to your smartphone.
Triglyceride-to-HDL Ratio After assessing each of these five biomarkers, there is one more step: calculate your triglyceride-to-HDL ratio to better understand insulin sensitivity. Simply divide your triglycerides by your HDL. Interestingly, studies have shown that this value correlates well with underlying insulin resistance. So even if you are unable to access a fasting insulin test, the triglyceride-to-HDL ratio can give you a general sense of where you’re at. According to Dr. Mark Hyman, “the triglyceride-to-HDL ratio is the best way to check for insulin resistance other than the insulin response test. According to a paper published in Circulation, the most powerful test to predict your risk of a heart attack is the ratio of your triglycerides to HDL. If the ratio is high, your risk for a heart attack increases sixteen-fold — or 1,600 percent! This is because triglycerides go up and HDL (or ‘good cholesterol’) goes down with diabesity.” Dr. Robert Lustig agrees: “The triglyceride-to-HDL ratio is the best biomarker of cardiovascular disease and the best surrogate marker of insulin resistance and metabolic syndrome.” In children, higher triglyceride-to-HDL is significantly correlated with mean insulin, waist circumferences, and insulin resistance. In adults, the ratio has shown a positive association with insulin resistance across normal weight and overweight people and significantly tracks with insulin levels, insulin sensitivity, and prediabetes. Perplexingly, the triglyceride-to-HDL ratio is not a metric used in standard clinical practice. If you remember one thing from this chapter, remember this: you need to know your insulin sensitivity. It can give you lifesaving clues about early dysfunction and Bad Energy brewing in your body, and is best assessed by a fasting insulin test, discussed below. Right now, this is not a standard test offered to you at your annual physical. I implore you to find a way to get a fasting insulin test or to calculate your triglyceri
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