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" "Clearly it’s important not to injure the septum during operations. So why is it happening repeatedly? ...[L]ikely ...improper myocardial protection (the technique used to protect the heart... that was my initial major medical discovery and quickly adopted worldwide). We... tested 119 consecutive patients and found no septum damage when protection was done correctly. ...Successful protection involves ...the cardioplegic solution and adopting a correct delivery strategy. ...[I]f surgeons are to prevent the all-too-frequent injury to the heart’s vital septum, they must avoid taking shortcuts that compromise this essential combination.
(September 29, 1935 - September 20, 2018) was a Distinguished Professor of Surgery, Division of Cardiothoracic Surgery, at the . His research interests initially centered in the area of myocardial protection and led to the introduction of blood , which is currently used by over 85% of surgeons in the United States and 75% of surgeons worldwide for adult and pediatric heart operations. He was a member of multiple surgical societies, including the , , and the .
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Today, wonderful operations can be performed on babies to repair heart defects. This includes "blue babies." During the corrective procedure, high levels of oxygen are typically administered by a heart-lung machine... But... lung and heart damage may worsen. ...[O]ne cause of the problem were the high levels of oxygen administered ...as toxic substances are produced when such oxygen concentrations are metabolized. Babies are particularly vulnerable... Yet we found this "re-oxygenation injury" could be avoided by lowering oxygen levels delivered... There was excellent recovery of heart function without lung or body swelling. ...A 2012 overview on reoxygenation injury was published in the World Journal for Pediatric and Congenital Heart Surgery that summarized international papers from others... [R]aising such questions to traditionalists garners vehement rejection, along with counterarguments that keeping oxygen levels high is a strategy ..."proven..." over many decades (since not all blue babies suffer damage...) They perceive the greater risk is losing the baby because of "insufficient... oxygen"... and... blame... unforeseen complications on other factors.
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