Muy sensible es la reacción de una comunidad de chimpancés en una jaula cuando un miembro de la familia toma LSD. Aunque en el propio animal no pueda… - Albert Hofmann

The rapid rise of drug use, which had its beginning in this country about twenty years ago, was not, however, a consequence of the discovery of LSD, as superficial observers often declared. Rather it had deep-seated sociological causes: materialism, alienation from nature through industrialization and increasing urbanization, lack of satisfaction in professional employment in a mechanized, lifeless working world, ennui and purposelessness in a wealthy, saturated society, and lack of a religious, nurturing, and meaningful philosophical foundation of life.

Experience of the world as matter, as object, to which man stands opposed, has produced modern natural science and technology — creations of the Western mind that have changed the world. With their help human beings have subdued the world. Its wealth has been exploited in a manner that may be characterized as plundering, and the sublime accomplishment of technological civilization, the comfort of Western industrial society, stands face-to-face with a catastrophic destruction of the environment. Even to the heart of matter, to the nucleus of the atom and its splitting, this objective intellect has progressed and has unleashed energies that threaten all life on our planet.

[Hallucinogenic drugs] now formed a circle, one could almost say a magic circle: the starting point had been the synthesis of lysergic acid amides, among them the naturally occurring ergot alkaloid ergobasin. This led to the synthesis of lysergic acid diethylamide, LSD. The hallucinogenic properties of LSD were the reason why the hallucinogenic magic mushroom teonanacatl found its way into my laboratory. THe work with teonanacatl, from which psilocybin and psilocin were isolated, proceeded to the investigation of another Mexican magic drug, ololiuhqui, in which hallucinogenic principles in the form of lysergic acid amides were again encountered, including ergobasin — with which the magic circle closed.