Certainly, there is no general principle that prevents the creation of an economic theory based on other hypotheses than that of rationality. - Kenneth Arrow

In view of the magnitude of an economic system, it would take only a very small percentage of improvement in economic stability or growth to make almost any conceivable data collection worthwhile. The situation is analogous to reported results of the use of linear programming in industry; the gains are small in proportion to previous profit levels but still very much larger than the costs of the programming. No country is adequate in respect to its data. In particular the underdeveloped countries, with their ambitious programs, might well ponder whether or not the marginal productivity of investment in better economic statistics is perhaps not higher than almost any conceivable alternative; they have more need and fewer data.

There’s a famous Churchill quote: “democracy is the worst form of government, except for all the others.” That applies to regulation as well. In the late 1800s, we had a natural monopoly: railroads. The government created a regulatory enterprise – the Interstate Commerce Commission – and of course it was captured. But it still made a difference.
I think we just have to accept that capture does occur, but it’s limited. The Federal Trade Commission, for example, is a pretty active body. Monopolies have been broken up. The AT&T telephone monopoly was broken up in 1982 – Stigler was still writing about regulatory capture then. AT&T was a classic monopoly, but a pretty benevolent one. It delivered good service – rates were too high, but not by that much. It didn’t necessarily pass on value to the consumers, but Bell Labs were a source of great innovative function. Nevertheless, it was broken up by antitrust measures, brought on by government.
So there is regulatory capture, but it is by no means complete. Regulations do play a role.
One example of non-regulatory capture fighting against effective regulation was during the run-up to the 2008 crash, when several officials argued for CDOs to be regulated, which means they would have had to meet certain requirements of transparency. This was not accepted. I’m not saying the crash could have been avoided if that happened, but that would have made a big difference.

To the extent that individuals are really individual, each an autonomous end in himself, to that extent they must be somewhat mysterious and inaccessible to each other. There cannot be any rule that is completely acceptable to all. There must, or so it now seems tome, be the possibility of unadjudicable conflict, which may show itself logically as paradoxes in the process of social decision-making.