When you come into a place, it is really important to see people who are achieving things,” Professor Osier said. “If you come into a place where people are dead wood, however brilliant you may be, you are going to become dead wood yourself.

Malaria still claims the lives of hundreds of thousands of children each year and has a major economic impact on the lives of many in sub-Saharan Africa. Children that survive severe malaria can be left with permanent physical disability that takes many forms.

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The Wellcome Trust has been instrumental to getting me established as a credible African research scientist. I competed and won a training fellowship that supported my PhD studies. My current work is supported by an intermediate fellowship, and this has enabled me to compete successfully for an MRC/DFID African Research Leader award.

My average day has evolved over the years as I have graduated from being a junior to a more senior researcher. Earlier on, I’d spend a lot of time in the laboratory generating data and less time in the office reading scientific literature, analysing data and writing up my work.

The closest comparison I can give is with COVID-19. When it hit Western countries, we all felt it: the pain of lockdown; of losing someone; of being ill ourselves. We felt that urgency, that we needed a vaccine and we needed it yesterday, so we said, ‘let's do it, let's do everything that we can’. For diseases that are far off, that sense of urgency is lost.

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The second angle of our research aims to understand how the immune system handles the complexity of the malaria parasite. For example, if it produces antibodies, we need to identify the parasite proteins to which the antibodies are binding and the mechanisms they are using. To do this, we probe the parasite with antibodies from people who have developed resistance to malaria parasite.