Kenyan immunologist, paediatrician and educator
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The second angle of our research aims to understand how the immune system handles the complexity of the malaria parasite. For example, if it produces antibodies, we need to identify the parasite proteins to which the antibodies are binding and the mechanisms they are using. To do this, we probe the parasite with antibodies from people who have developed resistance to malaria parasite.
The closest comparison I can give is with COVID-19. When it hit Western countries, we all felt it: the pain of lockdown; of losing someone; of being ill ourselves. We felt that urgency, that we needed a vaccine and we needed it yesterday, so we said, ‘let's do it, let's do everything that we can’. For diseases that are far off, that sense of urgency is lost.
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I joined the KEMRI-Wellcome Trust Research Programme in 1998 as a junior doctor and was interested in training in paediatrics. It was here that I was introduced to research on malaria in general, and begun to understand that we know so little about this disease that has been with humans for such a long time.