Malaria still claims the lives of hundreds of thousands of children each year and has a major economic impact on the lives of many in sub-Saharan Africa. Children that survive severe malaria can be left with permanent physical disability that takes many forms.

My average day has evolved over the years as I have graduated from being a junior to a more senior researcher. Earlier on, I’d spend a lot of time in the laboratory generating data and less time in the office reading scientific literature, analysing data and writing up my work.

I try to understand how adults in Africa learn to live in harmony with the parasite responsible for malaria, such that infections do not make them ill. This knowledge could help us design vaccines that would protect children, who can die as a result of a malaria infection.

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The Wellcome Trust has been instrumental to getting me established as a credible African research scientist. I competed and won a training fellowship that supported my PhD studies. My current work is supported by an intermediate fellowship, and this has enabled me to compete successfully for an MRC/DFID African Research Leader award.

I joined the KEMRI-Wellcome Trust Research Programme in 1998 as a junior doctor and was interested in training in paediatrics. It was here that I was introduced to research on malaria in general, and begun to understand that we know so little about this disease that has been with humans for such a long time.