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Bill Gates made a convincing argument for why improving human health is money well spent, and won't lead to overpopulation, in his 2018 video "Does S… - David A. Sinclair
" "Bill Gates made a convincing argument for why improving human health is money well spent, and won't lead to overpopulation, in his 2018 video "Does Saving More Lives Lead to Overpopulation?"56 The short answer is: No.
If we were to stop all deaths — every single one around the globe — right now, we would add about 150,000 people to our planet each day. That would be 55 million people each year. That might sound like a lot, but it would be less than a single percentage point. At that rate, we would add a billion people to our ranks every eighteen years, which is still considerably slower than the rate at which the last few billion people have come along and easily countered by the global decline in family sizes.
It's still an increase, but it's not the sort of exponential growth many people fret about when they first encounter the idea of slowing aging.
Recall, these calculations are what we'd face if we ended all deaths right away. And although I'm very optimistic about the prospects for prolonged vitality, I'm not that optimistic. I don't know any reputable scientist who is.
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David Andrew Sinclair
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Dr. David Sinclair
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David A Sinclair
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David Sinclair
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Additional quotes by David A. Sinclair
Like sirtuins, scientists have found TOR — called mTOR in mammals — in every organism in which they've looked for it. Like that of sirtuins, mTOR activity is exquisitely regulated by nutrients. And like the sirtuins, mTOR can signal cells in stress to hunker down and improve survival by boosting such activities as DNA repair, reducing inflammation caused by senescent cells, and, perhaps its most important function, digesting old proteins.27 When all is well and fine, TOR is a master driver of cell growth. It senses the amount of amino acids that is available and dictates how much protein is created in response. When it is inhibited, though, it forces cells to hunker down, dividing less and reusing old cellular components to maintain energy and extend survival — sort of like going to the junkyard to find parts with which to fix up an old car rather than buying a new one, a process called autophagy. When our ancestors were unsuccessful in bringing down a woolly mammoth and had to survive on meager rations of protein, it was the shutting down of mTOR that permitted them to survive.
Don't be disheartened by my claim that we are the biological equivalent of an old DVD player. This is actually good news. If Szilard had turned out to be right about mutations causing aging, we would not be able to easily address it, because when information is lost without a backup, it is lost for good. Ask anyone who's tried to play or restore content from a DVD that's had an edge broken off: what is gone is gone. But we can usually recover information from a scratched DVD. And if I am right, the same kind of process is what it will take to reverse aging.
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