There is no doubt that the human mind is fundamentally incapable of solving these formidable problems (the origin of life, nature of matter, origin o… - Santiago Ramón y Cajal

As Claude Bernard has pointed out, researchers cannot transcend the determinism of phenomena; instead, their mission is limited to demonstrating the how, never the why, of observed changes. This is a modest goal in the eyes of philosophy, yet an imposing challenge in actual practice.

The severe constraints imposed by determinism may appear to limit philosophy in a rather arbitrary way. However, there is no denying that in the natural sciences — and especially in biology — it is a very effective tool for avoiding the innate tendency to explain the universe as a whole in terms of general laws.

The unique method of reflection indulged in by the Pythagoreans and followers of Plato (and pursued in modern times by Descartes, Fichte, Krause, Hegel, and more recently at least partly by Bergson) involves exploring one’s own mind or soul to discover universal laws and solutions to the great secrets of life.