When asked to make the formal declaration that I did not intend to overthrow the Constitution of the United States, I was fool enough to reply that I had no such purpose, but that were I to do it by mistake I should be inexpressibly contrite.

The purpose of scientific enquiry is not to compile an inventory of factual information, nor to build up a totalitarian world picture of natural Laws in which every event that is not compulsory is forbidden. We should think of it rather as a logically articulated structure of justifiable beliefs about nature.

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Observation is the generative act in scientific discovery. For all its aberrations, the evidence of the senses is essentially to be relied upon—provided we observe nature as a child does, without prejudices and preconceptions, but with that clear and candid vision which adults lose and scientists must strive to regain.

We cannot point to a single definitive solution of any one of the problems that confront us — political, economic, social or moral, that is, having to do with the conduct of life. We are still beginners, and for that reason may hope to improve. To deride the hope of progress is the ultimate fatuity, the last word in poverty of spirit and meanness of mind. There is no need to be dismayed by the fact that we cannot yet envisage a definitive solution of our problems, a resting-place beyond which we need not try to go.

It can be said with complete confidence that any scientist of any age who wants to make important discoveries must study important problems. Dull or piffling problems yield dull or piffling answers. It is not enough that a problem should be "interesting" - almost any problem is interesting if it is studied in sufficient depth.

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Scientific discovery is a private event, and the delight that accompanies it, or the despair of finding it illusory, does not travel. One scientist may get great satisfaction from another’s work and admire it deeply; it may give him great intellectual pleasure; but it gives him no sense of participation in the discovery, it does not carry him away, and his appreciation of it does not depend on his being carried away. If it were otherwise the inspirational origin of scientific discovery would never have been in doubt.

In no sense other than an utterly trivial one is reproduction the inverse of chemical disintegration. It is a misunderstanding of genetics to suppose that reproduction is only 'intended' to make facsimiles, for parasexual processes of genetical exchange are to be found in the simplest living things.

The Phenomenon of Man stands square in the tradition of Naturphilosophie, a philosophical indoor pastime of German origin which does not seem even by accident (though there is a great deal of it) to have contributed anything of permanent value to the storehouse of human thought.

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