The concepts which now prove to be fundamental to our understanding of nature—a space which is finite; a space which is empty, so that one point [of … - James Hopwood Jeans

In the interior of the atom, Bohr had tried the plan of retaining the particle-electron and modifying the classical mechanics. Heisenberg took the opposite course, his procedure amounting in effect to retaining the classical mechanics, at least in form, and modifying the electron. Actually, the electron dropped out all together, because it exists only as a matter of inference and not of direct observation. For the same reason, the new theory contains no mention of atoms, nuclei, protons, or of electricity in any shape or form. The existences of all these are matters of inference, and Heisenberg's purely mathematical theory could no more make contact with them than with the efficiency of a turbine or with the price of wheat.

A similar situation occurred in astronomy, where the Newtonian law of gravitation had been found to predict the orbits of the outer planets with great accuracy, but had failed with the orbits of Mercury and Venus. The relativity theory of gravitation had provided the necessary modification of Newton's law, and in working out the details of the new theory, Einstein had utilized the fact that Newtonian law gave the right result at great distances from the sun. Heisenberg, confronted with a similar problem, was able to avail himself of the fact that the classical mechanics gave the right result at great distances from the atomic nucleus. Here, and here alone Heisenberg's theory made contact with the world of the older physics.

A second conspicuous landmark... is the enunciation of the fundamental law of radioactive disintegration by Rutherford and Soddy in 1903. This law was in no sense a consequence or development of Planck's theories; indeed fourteen years were to elapse before any connection was noticed between the two. The new law asserted that the atoms of radioactive substances broke up spontaneously, and not because of any particular conditions or special happenings. This seemed to involve an even more startling break with classical theory than the new laws of Planck; radioactive break-up appeared to be an effect without a cause, and suggested that the ultimate laws of nature were not even causal.