The world, unfortunately, rarely matches our hopes and consistently refuses to behave in a reasonable manner. - Stephen Jay Gould

Science is no inexorable march to truth, mediated by the collection of objective information and the destruction of ancient superstition. Scientists, as ordinary human beings, unconsciously reflect in their theories the social and political constraints of their times.

[G]enes make enzymes, and enzymes control the rates of chemical processes. Genes do not make “novelty seeking” or any other complex and overt behavior. Predisposition via a long chain of complex chemical reactions, mediated through a more complex series of life's circumstances, does not equal identification or even causation.

Our shenanigans, nuclear and otherwise, might easily lead to our own destruction in the foreseeable future. We might take most of the large terrestrial vertebrates with us—a few thousand species at most. We surely cannot extirpate 500,000 species of beetles, though we might make a significant dent. I doubt we could ever substantially touch bacterial diversity. The model organisms cannot be nuked into oblivion, or very much affected by any of our considerable conceivable malfeasances.