I do not dispute the right of individuals to look to religion for a private moral compass, but I do object to the assumption of too many religious pe… - James Watson

To make a huge success, a scientist must be prepared to get into deep trouble. Sometime or another, someone will tell you that you are not ready to do something. … If you are going to make a big jump in science, you will very likely be unqualified to succeed by definition. The truth, however, won't save you from criticism. Your very willingness to take on a very big goal will offend some people who will think that you are too big for your britches and crazy to boot.

The discovery of the double helix sounded the death knell for vitalism. Serious scientists, even those religiously inclined, realized that a complete understanding of life would not require the revelation of new laws of nature. Life was just a matter of physics and chemistry, albeit exquisitely organized physics and chemistry. The immediate task ahead would be to figure out how the DNA-encoded script of life went about its work.

The problem was insoluble: you cannot, we thought, have DNA without proteins, and you cannot have proteins without DNA.
RNA, however, being a DNA equivalent (it can store and replicate genetic information) as well as a protein equivalent (it can catalyze critical chemical reactions) offers an answer. In fact, in the “RNA world” the chicken-and-egg problem simply disappears. RNA is both the chicken and the egg.
RNA is an evolutionary heirloom. Once natural selection has solved a problem, it tends to stick with that solution, in effect following the maxim “if it ain’t broke, don’t fix it.” In other words, in the absence of selective pressure to change, cellular systems do not innovate and so bear many imprints of the evolutionary past. A process may be carried out in a certain way simply because it first evolved that way, not because that is absolutely the best and most efficient way.