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" "The observation of reduction in complexity in many groups or organisms after a structure has emerged in a full-blown state makes sense in terms of homeobox genes.
Jeffrey Hugh Schwartz (born March 6, 1948) is an American physical anthropologist and professor of biological anthropology at the University of Pittsburgh in Pittsburgh, Pennsylvania, and a fellow and President of the World Academy of Art and Science (WAAS) from 2008 to 2012. Schwartz' research involves the methods, theories, and philosophies in evolutionary biology, including the origins and diversification of primates. He has studied and analyzed human and primate skeletons and archaeological remains, focusing much of his research on dentofacial morphology. He has done substantial fieldwork and museum research in the collections of major museums around the globe.
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If Walter Garstang's suggestion is correct, and chordates did arise from a tunicate-like form by retaining the chordate features of their larval stage of development into adulthood, then the first chordates must have been affected by a regulatory mutation that kept the Manx gene activated for a longer period of time.