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" "A mechanistic model has the following advantages: 1. It contributes to our scientific understanding of the phenomenon under study. 2. It usually provides a better basis for extrapolation (at least to conditions worthy of further experimental investigation if not through the entire range of all input variables). 3. It tends to be parsimonious (i.e, frugal) in the use of parameters and to provide better estimates of the response
George Edward Pelham Box (October 18, 1919 – March 28, 2013) was a British mathematician and professor of statistics at the University of Wisconsin, and a pioneer in the areas of quality control, , design of experiments and . He was the son-in-law of Sir Ronald Fisher.
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An innovative discussion of building empirical models and the fitting of surfaces to data. Introduces the general philosophy of response surface methodology, and details least squares for response surface work, factorial designs at two levels, fitting second-order models, adequacy of estimation and the use of transformation, occurrence and elucidation of ridge systems, and more. Some results are presented for the first time. Includes real-life exercises, nearly all with solutions.