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" "Cells are required to stick precisely to the point. Any ambiguity, any tendency to wander from the matter at hand, will introduce grave hazards for the cells, and even more for the host in which they live. Minor inaccuracies may cause reactions in which neighboring cells are recognized as foreign, and done in. There is a theory that the process of aging may be due to the cumulative effect of imprecision, a gradual degrading of information. It is not a system that allows for deviating.
Lewis Thomas (25 November 1913 - 3 December 1993) was a physician, author, administrator, educator, policy advisor and researcher. He served as a Dean of Yale Medical School, Dean of the New York University School of Medicine and President of Memorial Sloan-Kettering Institute.
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I can think of a few microorganisms, possibly the tubercle bacillus, the syphilis spirochete, the malarial parasite, and a few others, that have a selective advantage in their ability to infect human beings, but there is nothing to be gained, in an evolutionary sense, by the capacity to cause illness or death. Pathogenicity may be something of a disadvantage for most microbes, carrying lethal risks far more frightening to them than to us. The man who catches a meningococcus is in considerably less danger for his life, even without chemotherapy, than meningococci with the bad luck to catch a man.
It is when physicians are bogged down by their incomplete technologies, by the innumerable things they are obliged to do in medicine when they lack a clear understanding of disease mechanisms, that the deficiencies of the health-care system are most conspicuous. If I were a policy-maker, interested in saving money for health care over the long haul, I would regard it as an act of high prudence to give high priority to a lot more basic research in biologic science.