I am infinitely saddened to find myself suddenly surrounded in the west by a sense of terrible loss of nerve, a retreat from knowledge into–into what… - Jacob Bronowski

We are all afraid - for our confidence, for the future, for the world. That is the nature of the human imagination. Yet every man, every civilization, has gone forward because of its engagement with what it has set itself to do. The personal commitment of a man to his skill, the intellectual commitment and the emotional commitment working together as one, has made the Ascent of Man.

Since the word "knowledge" occurs in my general title... I am going to be talking about epistemology, although I prefer to use the eighteenth-century, indeed, medieval phrase, "natural philosophy." ...that enterprise of the human mind which attempts to trace lawfulness to nature, dead and living, but which is not directed to specific inquiries into how this or that law works. Philosophy in the sense in which I practice it, natural philosophy, is concerned with lawfulness rather than with laws and the general nature of laws rather than with the specific structure of this or that law. Natural philosophy was one of the three topics (moral philosophy and metaphysical philosophy were the others) to which one graduated in medieval universities after having studied the seven liberal arts.
I believe that we need to review the whole of our natural philosophy in the light of scientific knowledge that has arisen in the last fifty years.

We cannot change our character, we can only enlarge it. If we are wise, then we go on learning all through life, and go on fitting what is new to what we have learnt before, piece by piece.