As you will never be sure which are the right problems to work on, most of the time that you spend in the laboratory or at your desk will be wasted. … - Steven Weinberg

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As you will never be sure which are the right problems to work on, most of the time that you spend in the laboratory or at your desk will be wasted. If you want to be creative, then you will have to get used to spending most of your time not being creative, to being becalmed on the ocean of scientific knowledge.