Inferences and large dosages of imagination actually have allowed the construction of a far more adequate understanding of the cosmic and human past … - William Hardy McNeill

With the historicization of the heavens the age-old idea of discovering universal laws of behavior applicable everywhere and always seems to have lost plausibility, whether for sub-atomic particles or for human beings. ...all such patterns and regularities, it seems to me, should be understood to be limited, local, evanescent — including, now, even the laws of physics.

Christian theology was a revised version of Greek philosophy and the effort Plato and his heirs made to discern the permanent behind the sensible, the Ideal and the Real behind the world of individual things — ever in flux, becoming and decaying and never, ever reliably and completely True.

Painting responded to the plague-darkened vision of the human condition provoked by repeated exposure to sudden, inexplicable death. Tuscan painters reacted against Giotto's serenity, preferring sterner, hieratic portrayals of religious scenes and figures. The "Dance of Death" became a common theme for art; and several other macabre motifs entered the European repertory.