"It is inevitable, therefore, that some approaches to politics, economics, science, and even spirituality and ethics will be objectively better than their competitors (by any measure of "better" we might wish to adopt), and gradations here will translate into very real differences in human happiness."
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If our well-being depends upon the interaction between events in our brains and events in the world, and there are better and worse ways to secure it, then some cultures will tend to produce lives that are more worth living than others; some political persuasions will be more enlightened than others; and some world views will be mistaken in ways that cause needless human misery.
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