Honey bees, too, use a highly specialized learning mechanism to help them figure out where they are going: the difference is that their system works … - Gary F. Marcus

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Honey bees, too, use a highly specialized learning mechanism to help them figure out where they are going: the difference is that their system works based on the trajectory of a single star, our very own sun. Once again, part of the system is prewired, but part of it requires learning. The prewired bit is a mathematical function that relates the sun's position on the horizon to to a bee's orientation-but some of the values of the equation must be set, which is where learning comes in. What the bee learns is a highly specific bit of information about the sun's trajectory at the bee's particular latitude at a particular time of year. A five o'clock winter sun in Boston means something very different from a five o'clock summer sun in California, and a highly focused learning mechanism allows honeybees to take advantage of that information. We know that bees don't simply memorize a correspondence between particular places on the horizon and particular headings, because bees that have been raised in conditions in which they are exposed only to morning light can accurately use the sun as a guide during evening light.

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Cell differentiation can turn neurons into everything from clocks that control circadian rhythms to photoreceptors that convert light into electrical-chemical impulses or decision makers that tally votes and decide courses of action. In the retina (often used as a case study because it can be directly and naturally stimulated), there are at least fifty different kinds of neurons specialized to different tasks, such as looking for motion, recognizing colors, detecting objects in low light, and measuring brightness and contrast. In the brain as a whole, there may be as many as 10,000 different kinds of neurons, each contributing to a different aspect of mental life.

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What propels an embryo from one stage to the next-and makes one species different from another-is not a blueprint but rather an enormous autonomous library of the instructions contained within its genome. Each gene does double duty, specifying both a recipe for a protein and a set of regulatory conditions for when and where it should be built. Taken together suites of these IF-THEN genes give cells the power to act as parts of complicated improvisational orchestras. Like real musicians, what they play depends on both their own artistic impulses and what the other members of the orchestra are playing. As we will see in the next chapter, every bit of this process-from the Cellular Big 4 to the combination of regulatory cues-holds as much for development of the brain as it does for the body.

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