I can now rejoice even in the falsification of a cherished theory, because even this is a scientific success. - John Carew Eccles

The concept of substance leads to a materialist aspect of the mind. I speak instead of the spiritual existence of the self without mentioning any 'substance' properties. The great problem is 'how the self controls its brain'. This is dualistic, but not in terms of two substances. Instead it relates to the two worlds of Popper.

I have read a great deal now on the neurological side and much on the anthropological side and on the philosophical side and we have had all these discussions and all the time I have the feeling that something may break. I mean that some little light at the end of the tunnel may be sensed or some flash of insight may come. I of course know very well that there is no guarantee it will come, but I have already got myself into this state of expectancy that something will come to my imagination which has some germ of truth about it in this most difficult field.

In order that a "self" may exist there must be some continuity of mental experiences and, particularly, continuity bridging gaps of unconsciousness. For example, the continuity of our "self" is resumed after sleep, anaesthesia, and the temporary amnesias of concussion and convulsions.