For Robin Marantz Henig, a columnist at the New York Times,… - David A. Sinclair

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For Robin Marantz Henig, a columnist at the New York Times, the "bitter truth" about mortality came late in life, after she became a grandparent. "Beneath all the wonderful moments you may be lucky enough to share in and enjoy," she wrote, "your grandchild's life will be a long string of birthdays you will not live to see."3

David A. Sinclair

Lifespan: The Revolutionary Science of Why We Age—and Why We Don't Have To · September 10, 2019 Verified in 1 source Sign up to see the complete provenance

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Alternative Names: David Andrew Sinclair • Dr. David Sinclair • David A Sinclair • David Sinclair

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Atul Gawande Lewis Thomas Michael Crichton Matt Ridley Bret Weinstein

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Every one of our cells has the same DNA, of course, so what differentiates a nerve cell from a skin cell is the epigenome, the collective term for the control systems and cellular structures that tell the cell which genes should be turned on and which should remain off. And this, far more than our genes, is what actually controls much of our lives.

Youth → broken DNA → genome instability → disruption of DNA packaging and gene regulation (the epigenome) → loss of cell identity → cellular senescence → disease → death.

1800, the global literacy rate was 12 percent, by 1900 it was 21 percent, and today it's 85 percent.

For Robin Marantz Henig, a columnist at the New York Times, the "bitter truth" about mortality came late in life, after she became a grandparent. "Be… - David A. Sinclair

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Additional quotes by David A. Sinclair