Instead, in our world, nature's contribution to development comes not by providing a finely detailed sketch of a finished product, but by providing a… - Gary F. Marcus

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Instead, in our world, nature's contribution to development comes not by providing a finely detailed sketch of a finished product, but by providing a complex system of self-regulating recipes. Those recipes provide for many different things-from the construction of enzymes and structural proteins to the construction of motors, transporters, receptors, and regulatory proteins-and thus there is no single, easily characterizable genetic contribution to the mind. In the ongoing, everyday functioning of the brain, genes supervise the construction of neurotransmitters, the metabolism of glucose, and the maintenance of synapses. In early development, they help to lay down a rough draft, guiding the specialization and migration of cells as well as the initial pattern of wiring. In synaptic strengthening, genes are a vital participant in a mechanism by which experience can alter the wiring of the brain (thereby influencing the way that an organism interprets and responds to the environment). There are at least as many different genetic contributions to the mind and brain as there are genes; each contributes by regulating a different process.

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Biology doesn't know in advance what the end product will be; there's no Stuffit Compressor to convert a human being into a genome. But the genome itself is very much akin to a compression scheme, a terrifically efficient description of how to build something of great complexity-perhaps more efficient than anything yet developed in the labs of computer scientists (never mind the complexities of the brain, there are trillions of cells in the rest of the body, and they are all supervised by the same 30,000-gene genome). And although there is no counterpart in nature to a program that compresses a picture into a compact description, there is a natural counterpart to the program that decompresses the compressed encoding, and that's the cell. Genome in, organism out. Through the logic of gene expression, cells are self-regulating factories that translate genomes into biological structure.

Our sense of a composition largely inheres in how we feel about the individual parts; narrative arcs are almost always essential in drama but (unless there are lyrics involved) often less essential in music. All of this is, I suspect, again symptomatic of human memory limitations. We live, to a remarkable degree, in the present; what happened thirty seconds ago is already rapidly fading from our memory (or at least rapidly becomes harder for us to retrieve).

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"Repetition sometimes works in poetry, but rarely in prose. The musical provocateur John Cage once wrote a lecture in which a single page was repeated fourteen times, with the refrain "If anybody is sleep let him go to sleep" (Cage, 1961). Midway through, the artist Jean Reynal stood up and screamed, "John, I dearly love you, but I can't bear another minute.

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