I do like this quote from Simon Conway Morris that if the aliens call then don't pick up the phone. I'm not sure I'd really like to meet any of them … - Nick Lane

I'm... interested in the principles of what governs the emergence of life on the planet, with a certain set of resources. Can we understand it? We'll never know what happened, so we'll never know how life started on earth. ...[I]f those principles are enormously difficult, if it turns out that it's a freak statistical accident, then there's little point in studying it and we will gain... very little. If, on the other hand, those principles are reasonable, intelligible, that we can study them in the lab and demonstrate that the steps that we propose are plausible and... we can demonstrate it, then I think that's as close to understanding the origin of life [as] we can get. ...[I]f those principles are generalizable, then as a scientist, that's... a pleasing thing. I'm not sure there's any more that's more pleasing to me, personally as a scientist.

I read some of those ideas years ago, , and thought it was thrilling. Over recent years I don't really see the need for a kind of genetic intermediary between an RNA level of genetic replication and some other form of replicator. ...[T]here's no suggestion that it's there in biology. There's no suggestion that I know from geology that is capable of giving rise to more complex systems, or to having an organic takeover. It seems to add in a layer of unnecessary complexity. So I much prefer to get straight into organic chemistry, and straight into as we know it.

The information encoded in DNA spells out the molecular structure of s. This, said Crick, is the 'central dogma' of all biology: genes code for proteins.